December 20, 2017
University of California, Berkeley scientists have for the first time used CRISPR-Cas9 gene editing to disable a defective gene that causes amyotrophic lateral sclerosis, or Lou Gehrig’s disease, in mice, extending their lifespan by 25 percent.
The therapy delayed the onset of the muscle wasting that characterizes the disease, which results in progressive weakness and eventually proves fatal when the muscles that control breathing fail.
This step toward a CRISPR cure for human ALS will be reported Dec. 20 in the journal Science Advances.
Read more from Berkeley News | December 20th, 2017: https://news.berkeley.edu/2017/12/20/first-step-toward-crispr-cure-of-lo...